The nasolabial fold is the crease that goes from the base of the nose to the sides of the mouth. It is created by loss of bone in the upper jaw bone (maxilla) and by sagging of the soft tissues in the midface & cheek. It is rare that this area is treated in isolation, but rather as part of holistically treating the middle third of the face. Often by correcting volume loss and sagging in the midface and jawline, the nasolabial fold is softened. This can be further improved by strategic placement of filler whilst still allowing for natural facial expression.